Sodium Valproate: The Forgotten Anti-Neuropathic Medication
نویسنده
چکیده
Neuropathic pain is a disabling chronic condition. Current international guidelines for the management of neuropathic pain include the use of anti-depressants and anti-epileptic medications, including amitriptyline (tricyclic anti-depressants), duloxetine (serotonin noradrenaline reuptake inhibitor), gabapentin (antiepileptic) and pregabalin (anti-epileptic) [1]. Opioids are mentioned but the guidelines state stronger doses are required as the nature of neuropathic pain is not as responsive to narcotic analgesics and the evidence is limited to peripheral neuropathic conditions. Tramadol and Tapentadol are also options that are considered in the management of neuropathic pain [2].
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